Table 1 Eight research groups funded under a PCORI Asthma Disparities Program for African Americans and Latinos

ASIST (Asthma Symptom-based adjustment of Inhaled Steroid Therapy in African American children)

St. Louis, MO

Kaharu Sumino, MD, MPH

206 African American children 6–17 yo with mild to moderate asthma

Randomized, open-label, parallel group pragmatic trial with randomization to receive either symptom-based adjustment or physician-based adjustment of asthma medications. PMID: 31371165 [33]

BEAMS (Breath with Ease: A Unique Approach to Managing Stress)

Washington, DC

Stephen Teach, MD, MPH

217 African American child-parent pairs. Children were 4-17yo with asthma. All had public insurance

Single-blind, prospective, RCT comparing usual care (guideline-based care with education and short-term care coordination) with usual care plus parental stress management. PMID: 31545115 [34]

Using Information Technology to Improve Access, Communication and Asthma in African American and Hispanic/Latino Adults

Philadelphia, PA

Andrea Apter, MD

301 African American and Hispanic/Latino adults with moderate to severe asthma

RCT comparing asthma control in patients receiving patient portal training plus home visits from CHW and patient portal training alone. PMID: 31181221 [35]

SAMBA (supporting asthma self-management behaviors in aging adults)

New York, NY

Alex Federman, MD, MPH

405 adults with moderate to severe asthma age 60 and older

Pragmatic RCT examining effectiveness of home and clinic-based program (SAMBA) compared with usual care for patients with moderate to severe asthma. PMID: 31180474 [36]

CHICAGO (Coordinated Healthcare Interventions for Childhood Asthma Gaps in Outcomes)

Chicago, IL

Jerry Krishnan, MD, PhD

373 children with asthma age 5–11 yo presenting to the ED with uncontrolled asthma

Multicenter trial comparing 3 discharge approaches for children presenting to ED with uncontrolled asthma (guideline based, ED only discharge instructions; guideline-based ED discharge instructions + home visits; enhanced usual care). PMID: 28366780 [37]

HIITBAC (Houston Home-based Integrated Intervention Targeting Better Asthma Control) for African Americans

Houston, TX

Winifred Hamilton, MS, PhD

263 African American adults with poorly controlled asthma

Randomized pragmatic trial comparing effectiveness of enhanced clinical care with and without home visits on asthma outcomes. PMID: 32151753 [13]

G2P (Guidelines to Practice: Reducing Asthma Health Disparities through Guideline Implementation)

Seattle, WA

James Stout, MD, MPH

551 children and adults with Medicaid 5–75 years of age with not well or poorly controlled asthma

RCT comparing effectiveness of CHW home visits with no CHW home visits on asthma outcomes. PMID: 27789250 [38]

Respiro Sano (Comparing Programs to Improve Asthma Control and Quality of Life for Latino Youth Living in Rural Areas and Their Caregivers)

San Diego, CA

John Elder, PhD, MPH

400 Latino children 6–17 years of age with mild, moderate, or severe persistent asthma in rural areas near California-Mexico border

2 × 2 factorial study nested within community intervention comparing approaches to improving asthma outcomes and quality of life (community program only, community program plus family program, community program plus clinic program, community program plus family and clinic programs). PMID: 27789250 [38]